The Smallest Patients Are at Greatest Risk From Radiation Exposure During MBSS.2,3
- Developing cells are more sensitive to radiation exposure2
- Children’s longer life expectancy increases the likelihood of developing radiation-related cancer2
In a study, female infants exposed to 100 mGy of X-rays were found to have a cancer risk of 634 per 100,000 versus 115 for male infants and four for 50-year-old women.2

VARIBAR® (barium sulfate) Can Help Maximize the Benefit/Risk Ratio of MBSS.

Smaller Bodies May Require Greater Magnification—and Exposure.1,2

The size of structures being imaged in young children is smaller and often requires magnification, with increased radiation exposure.2 They also have more soft tissue versus adult ossified cartilage so they may require a different beam quality and/or filtration to allow for sufficient image contrast. Using a standardized method for conducting an MBSS can help minimize time and radiation exposure.1
As Low As Reasonably Achievable…
Although the radiation dose from MBSS is relatively low, any radiation from medical tests must be minimized to comply with the “As Low As Reasonably Achievable” principle.3
This is particularly true in the pediatric population, especially infants. Since adverse effects of radiation exposure are known to be age-dependent, children are more sensitive to radiation-induced cancer than are adults. The risk of developing a radiation-related cancer is higher for a young child compared to an adult exposed to an identical radiation dose.10


For All Ages
VARIBAR THIN LIQUID, NECTAR, and THIN HONEY formulations are indicated for pediatric patients.5,7,8

For Pediatric Patients 6 Months and Older
VARIBAR HONEY and PUDDING are indicated for baby-food ready pediatric patients.4,6
Do I have to prepare VARIBAR products?
*VARIBAR® THIN LIQUID (barium sulfate) for oral suspension is supplied as a powder and constituted to a standard volume with water.
How important is VARIBAR standardization for pediatric patients?
VARIBAR® products offer a standard 40% w/v ratio of barium sulfate concentration across the product line, helping you get the same visualization from each swallowing event, test after test, no matter what viscosity level.4–8
Can VARIBAR THIN LIQUID (barium sulfate) for oral suspension be warmed?
Is VARIBAR indicated for use in pre-term babies?
THIN LIQUID (barium sulfate) for oral suspension are broadly indicated for use in pediatric patients.4–8
How do VARIBAR products taste?
With VARIBAR® products, each viscosity is formulated to provide pleasant, easily tolerated flavors, textures, and consistencies to help elicit normal salivation and a more natural swallowing action. The pleasing apple and vanilla flavors help increase patient acceptance and compliance.
To learn more about VARIBAR, click here.
Articles that mention VARIBAR products being used for pediatric patients
BaByVFSSImP© A Novel Measurement Tool for Videofluoroscopic Assessment of Swallowing Impairment in Bottle-Fed Babies: Establishing a Standard

Bonnie Martin-Harris, Kathryn A Carson, Jeanne M Pinto, Maureen A Lefton-Greif
INDICATIONS AND USAGE | IMPORTANT SAFETY INFORMATION
VARIBAR® (barium sulfate)
IMPORTANT SAFETY INFORMATION:
For Oral Administration. This product should not be used in patients with known or suspected perforation of the GI tract, known obstruction of the GI tract, high risk of aspiration, or hypersensitivity to barium sulfate products. Rarely, severe allergic reactions of anaphylactoid nature have been reported following administration of barium sulfate contrast agents. Aspiration may occur during the modified barium swallow examination, monitor the patient for aspiration.
INDICATIONS AND USAGE | IMPORTANT SAFETY INFORMATION
VARIBAR® (barium sulfate)
Indications and Usage:
VARIBAR® THIN HONEY (barium sulfate) oral suspension, VARIBAR® NECTAR (barium sulfate) oral suspension, and VARIBAR® THIN LIQUID (barium sulfate) for oral suspension, are indicated for use in modified barium swallow examinations to evaluate the oral and pharyngeal function and morphology in adult and pediatric patients. VARIBAR® HONEY (barium sulfate) oral suspension and VARIBAR® PUDDING (barium sulfate) oral paste are indicated for use in modified barium swallow examinations to evaluate the oral and pharyngeal function and morphology in adult and pediatric patients 6 months of age and older.
IMPORTANT SAFETY INFORMATION:
For Oral Administration. This product should not be used in patients with known or suspected perforation of the GI tract, known obstruction of the GI tract, high risk of aspiration, or hypersensitivity to barium sulfate products. Rarely, severe allergic reactions of anaphylactoid nature have been reported following administration of barium sulfate contrast agents. Aspiration may occur during the modified barium swallow examination, monitor the patient for aspiration.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.
Please consult full Prescribing Information for VARIBAR HONEY here, for VARIBAR THIN HONEY here, for VARIBAR PUDDING here, for VARIBAR NECTAR here, and for VARIBAR THIN LIQUID here.
VARIBAR is manufactured by E-Z-EM Canada Inc., for E-Z-EM, Inc., a subsidiary of Bracco Diagnostics Inc., Monroe Twp., NJ 08831.
VARIBAR is a registered trademark of E-Z-EM, Inc.
References:
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Steele CM, Martin-Harris B, Gosa M, Edwards Allen S. Diagnosis and Management of Swallowing Physiology: Standardized Contrast, the MBSImP™ & the IDDSI Framework. Appl Radiol. https://appliedradiology.com/articles/diagnosis-and-management-of-swallowing-physiology-standardized-contrast-the-mbsimp-the-iddsi-framework.
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McGhee K. Making an important pediatric diagnostic test easier to swallow. Medical University of South Carolina. April 20, 2020. https://web.musc.edu/about/news-center/2020/04/20/bonilha-swallow-study.
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Strauss KJ, Kaste, SC. The ALARA (as low as reasonably achievable) concept in pediatric interventional and fluoroscopic Imaging: Striving to keep radiation doses as low as possible during fluoroscopy of pediatric Patients—a white paper executive summary. Pediatr Radiol. 2006 Sep;36(Suppl 2):110-112. https://pubmed.ncbi.nlm.nih.gov/17412149/.
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VARIBAR® HONEY (barium sulfate) oral suspension full Prescribing Information. Monroe Twp., NJ: Bracco Diagnostics Inc.; March 2018.
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VARIBAR® NECTAR (barium sulfate) oral suspension full Prescribing Information. Monroe Twp., NJ: Bracco Diagnostics Inc.; February 2018.
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VARIBAR® PUDDING (barium sulfate) oral paste full Prescribing Information. Monroe Twp., NJ: Bracco Diagnostics Inc.; Oct. 2016.
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VARIBAR® THIN HONEY oral suspension full Prescribing Information. Monroe Twp., NJ: Bracco Diagnostics Inc.; January 2018.
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VARIBAR® THIN LIQUID (barium sulfate) for oral suspension full Prescribing Information. Monroe Twp., NJ: April 2019.
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Martin-Harris B, Carson KA, Pinto JM, Lefton-Greif MA. BaByVFSSImP© A Novel Measurement Tool for Videofluoroscopic Assessment of Swallowing Impairment in Bottle-Fed Babies: Establishing a Standard. Dysphagia. 2020 Feb;35(1):90-98.
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Radiation Risks and Pediatric Computed Tomography (CT): A Guide for Health Care Providers. National Cancer Institute. Sept 2018. https://www.cancer.gov/about-cancer/causes-prevention/risk/radiation/pediatric-ct-scans.
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Data on file. Bracco Diagnostics Inc. July 2022.